Read this regarding osteoporosis:

Prog Lipid Res. 1997 Sep;36(2-3):131-51. Related Articles, Links


Calcium metabolism, osteoporosis and essential fatty acids: a review.

Kruger MC, Horrobin DF.

Department of Physiology, University of Pretoria, South Africa.

Essential fatty acid (EFA)-deficient animals develop severe osteoporosis coupled with increased renal and arterial calcification. This picture is similar to that seen in osteoporosis in the elderly, where the loss of bone calcium is associated with ectopic calcification of other tissues, particularly the arteries and the kidneys. Recent mortality studies indicate that the ectopic calcification may be considerably more dangerous than the osteoporosis itself, since the great majority of excess deaths in women with osteoporosis are vascular and unrelated to fractures or other bone abnormalities. EFAs have now been shown to increase calcium absorption from the gut, in part by enhancing the effects of vitamin D, to reduce urinary excretion of calcium, to increase calcium deposition in bone and improve bone strength and to enhance the synthesis of bone collagen. These desirable actions are associated with reduced ectopic calcification. The interaction between EFA and calcium metabolism deserves further investigation since it may offer novel approaches to osteoporosis and also to the ectopic calcification associated with osteoporosis which seems to be responsible for so many deaths.

Publication Types:
Review

PMID: 9624425 [PubMed - indexed for MEDLINE]

This should tell you what is really behind osteoporosis. Where don't they get osteoporosis?.... In third world countries.

Gary :c)

I didn't read the article in detail but I am guessing "exercise" such as fishing, farming and working the land had something to do with the lower incidence of osteoporosis? In addiiton to lifestyle differences, I would also throw in some dietary effects as well. How is that? :wink:

I would also jump to say that a reason behind fewer incidents of osteoporosis in the past had to do with the expected lifespan, and agreed, dietary effects.

Women are more prone to osteoporosis after menopause for various reasons ranging from decreased estrogen to decreased physical activity. However, in the past, if menopause occurred around the same age as it does today, women were not typically living as long, and therefore, dying before serious signs of osteoporosis could surface. Also, the activity level of both men and women has notably dropped in the years past. When we move, our body stimulates bone building to occur and so there is a good chance this lessened past incidents of osteoporosis.

Also, when you consider how many additives and hormones we have in our foods today vs. in the past, there could quite possibly be a correlation with increased osteoporosis. Recent research has shown that males and females are maturing, on average, at a faster rate today than years past (which could eventually lead to earlier menopause in women?). Could that quite possibly be from the growth hormones used in our food supply? We have only begun to see the effects of other food additives on our bodies, which in years past, were not an issue. Perhaps these additives will correlate to problems in the years to come.

There has also been some research to show that diets high in proteins lead to problems with calcium absorption, as do alcohol, smoking, excessive salt, and oxalic acid (found in Swiss chard, chocolate, spinach, etc). With thousands of people on Atkins, increased serving sizes in food and drink, and unexpected sources of sodium (like canned foods and frozen dinners), our food supply does not volunteer itself to decreasing some of the risks invovled. However, like all research in nutrition, the jury is still out.

One major factor that has been overlooked when it comes to osteoperosis is GLUTATHIONE levels.
Remember that word GLUTATHIONE and do your own research on it and any other disease besides osteoperosis.

But first this is an exerpt from one document at the National Library of Medicine.

"Cells depleted of intracellular glutathione were more susceptible to cell death.
These results provide evidence that increased oxidative stress with aging makes chondrocytes more susceptible to oxidant-mediated cell death through the dysregulation of the glutathione antioxidant system. This may represent an important contributing factor to the development of osteoarthritis in older adults."

More here...
http://www.ncbi.nlm.nih.gov/entrez/query.f...t_uids=14673993

Plus over 1100 more related documents here at the National Library of Medicine
http://www.ncbi.nlm.nih.gov/entrez/query.f...om_uid=14673993

Just remember, Glutathione (glue-ta-thigh-own) aka GSH and use the search box at the Library there and any other disease. For better result, don't use comma's.

Please post any comments.

Randy

I think we are getting "osteoporosis" mixed up with "osteoarthritis". They mean two different things.

Achi

[edited by Ian - fixed the quotes]

Ooops, got all my quotes mixed up :oops:
Hope the message is still useful.
Achi

Hi Achi,

Don't worry. I'm following.

Judy

I am sorry I wasn't clearer on my last posting. The major point is antioxidants, oxidative stress and depleted glutathione. No matter the issue Glutathione is the key.
The links I posted before are vague and when it comes to the Library of Medicine some or most of the documents are just abstracts that don't explain much at all.

This link is about:
Marked decrease in plasma antioxidants in aged osteoporotic women: results of a cross-sectional study.

http://www.ncbi.nlm.nih.gov/entrez/query.f...t_uids=12679433

This one is...
Correlation between serum glutathione reductases and bone densitometry values
http://www.ncbi.nlm.nih.gov/entrez/query.f...st_uids=1821134

This next link provides 115 medical documents touching on topics from:
A duality in the roles of reactive oxygen species with respect to bone metabolism.
Clin Chim Acta. 2002 Apr;318(1-2):145-8.
PMID: 11880125 [PubMed - indexed for MEDLINE]

To:
Serum osteocalcin and bone alkaline phosphatase in healthy children in relation to age and gender.
Med Wieku Rozwoj. 2002 Jul-Sep;6(3):257-65. Polish.
PMID: 12637780 [PubMed - indexed for MEDLINE]

http://www.ncbi.nlm.nih.gov/entrez/query.f...om_uid=11880125

What has resently been dicovered is how to put the building blocks (pre cursors) of cellular glutathione together in a natural form for human consumption.

I would like to elaborate more if I may but it would require me to expost a medical discover at McGill University that has since been granted medical method of use patents and is now in production. So I would then be promoting a product which I believe is not allowed here.
But there are documents at the National Library of Medicine that I might be able to post here if given permission.

Randy

Related Links

Osteoporosis Web Sites


http://www.chronicdisease.org/Osteo_Counci...osteo_links.htm

http://www.pubmedcentral.nih.gov/articlere...gi?artid=193670

Randy