Resveratrol is an an Antiaging Product.It is an Antioxidant.It is found in the skin of certain plants such as red grapes, raspberries, mulberries, blueberries, cranberries and red wine.It has numerous health benefits, promotes a healthy longer life to consumers, and is free from unwanted side effects.In the research ,it is found that Resveratrol has anti aging property and it can help prevent heart disease and cancer.

Resveratrol
Resveratrol wine
Acai Berry Fruit

Hi 4Lucy,

It is good that you are contributing something to this forum, but it is even better if you tell people things that have been proven, instead of just what some manufacturer wants you to tell them so they can sell more product.

Your website link said......"Resveratrol is often touted as the ultimate fountain of youth. Scientific laboratory experiments confirm these claims and establish resveratrol as having the potential to increase longevity and improve health owing to the unusual antioxidant properties of the substance. While the product is excellent beyond doubt, here are 3 tips that'll help you derive the maximum out of this wonder of nature:

1. Go For Genuine Products

I am sure none of you would want to go through the trauma of landing up buying something that is grossly different from what you thought it would be like. It becomes important then to ensure that you are not getting grape seed extract or red wine extract in the name of resveratrol supplements. These undoubtedly contain resveratrol but the concentration is so low, it will not deliver any benefits at all.

2. Avoid Falling For The Hype

Anti ageing products always have a certain aura around them. Whether it is anti-ageing creams or supplements, they are bound to sell like hotcakes. In such a situation, one needs to understand that all the hype is mere eyewash. It is foolish to draw conclusion unless you actually try a product."

Some research has indicated that in the future resveratrol may offer protection to humans for some specific thing such as cardio protection but it still has not been proven for humans, and until it is you can not say it has been proven, regardless of what your boss wants you to say.


Nature. 2006 Nov 16;444(7117):280-1.

Resveratrol improves health and survival of mice on a high-calorie diet.
Baur JA, Pearson KJ, Price NL, Jamieson HA, Lerin C, Kalra A, Prabhu VV, Allard JS, Lopez-Lluch G, Lewis K, Pistell PJ, Poosala S, Becker KG, Boss O, Gwinn D, Wang M, Ramaswamy S, Fishbein KW, Spencer RG, Lakatta EG, Le Couteur D, Shaw RJ, Navas P, Puigserver P, Ingram DK, de Cabo R, Sinclair DA.

Department of Pathology, Paul F. Glenn Laboratories for the Biological Mechanisms of Aging, Harvard Medical School, 77 Avenue Louis Pasteur, Boston, Massachusetts 02115, USA.

Resveratrol (3,5,4'-trihydroxystilbene) extends the lifespan of diverse species including Saccharomyces cerevisiae, Caenorhabditis elegans and Drosophila melanogaster. In these organisms, lifespan extension is dependent on Sir2, a conserved deacetylase proposed to underlie the beneficial effects of caloric restriction. Here we show that resveratrol shifts the physiology of middle-aged mice on a high-calorie diet towards that of mice on a standard diet and significantly increases their survival. Resveratrol produces changes associated with longer lifespan, including increased insulin sensitivity, reduced insulin-like growth factor-1 (IGF-I) levels, increased AMP-activated protein kinase (AMPK) and peroxisome proliferator-activated receptor-gamma coactivator 1alpha (PGC-1alpha) activity, increased mitochondrial number, and improved motor function. Parametric analysis of gene set enrichment revealed that resveratrol opposed the effects of the high-calorie diet in 144 out of 153 significantly altered pathways. These data show that improving general health in mammals using small molecules is an attainable goal, and point to new approaches for treating obesity-related disorders and diseases of ageing.

PMID: 17086191 [PubMed - indexed for MEDLINE

They were mice in the experiments, so it may not even work for rats.


Look at this one.....



* Oxford Journals
* Life Sciences & Medicine
* Toxicological Sciences
* Volume 110, Number 1
* Pp. 61-67



ToxSci Advance Access originally published online on April 17, 2009
Toxicological Sciences 2009 110(1):61-67; doi:10.1093/toxsci/kfp079

© The Author 2009. Published by Oxford University Press on behalf of the Society of Toxicology. All rights reserved. For permissions, please email: journals.permissions@oxfordjournals.org
Resveratrol Inhibits Dioxin-Induced Expression of Human CYP1A1 and CYP1B1 by Inhibiting Recruitment of the Aryl Hydrocarbon Receptor Complex and RNA Polymerase II to the Regulatory Regions of the Corresponding Genes
Sudheer R. Beedanagari*, Ilona Bebenek*, Peter Bui* and Oliver Hankinson*,{dagger},1

* Molecular Toxicology Program, Dept of Pathology and Lab Medicine, Jonsson Comprehensive Cancer Center {dagger} Molecular Biology Institute, University of California, Los Angeles, California 90095

1 To whom the correspondence should be addressed at Department of Pathology and Lab Medicine, Box 951732, Center for Health Sciences, University of California, Los Angeles, Los Angeles, CA 90095-1732. Fax: (310) 794-9272. E-mail: ohank@mednet.ucla.edu.

Received January 12, 2009; accepted March 31, 2009


Abstract

The CYP1A family of cytochrome P450s (CYPs), comprising CYP1A1, CYP1A2, and CYP1B1, plays a role in bioactivation of several procarcinogens to carcinogenic derivatives, and also in detoxification of several xenobiotic compounds. Resveratrol (3,4,5-trihydroxystelbine) is a naturally occurring compound that has been shown in a number of studies to inhibit the induction of CYP1A1 and CYP1B1 by dioxin (2,3,7,8-tetrachloro-dibenzo-p-dioxin), but the mechanism(s) of resveratrol inhibition is controversial. In the current study, 100nM dioxin treatment for 24, 48, and 72 h induced CYP1A1, CYP1A2, and CYP1B1 mRNA levels in the human breast cancer cell line MCF-7, and CYP1A1 and CYP1A2 mRNA levels in the human hepatocellular carcinoma cell line, HepG2. Simultaneous treatment with 10µM resveratrol significantly inhibited dioxin-induced mRNA expression levels of these genes in both cell lines. Our studies are novel in that we used the chromatin immunoprecipitation assay to assay dioxin-induced recruitment of the aryl hydrocarbon receptor (AHR), and aryl hydrocarbon nuclear translocator (ARNT) to the enhancer regions and recruitment of RNA polymerase II to the promoter regions, of the CYP1A1 and CYP1B1 genes in their natural chromosomal settings. These recruitments were significantly inhibited in cells cotreated with resveratrol. Our studies thus indicate that resveratrol inhibits dioxin induction of the CYP1 family members either by directly or indirectly inhibiting the recruitment of the transcription factors AHR and ARNT to the xenobiotic response elements of the corresponding genes. The reduced transcriptional factor binding at their enhancers then results in reduced pol II recruitment at the promoters of these genes.

Key Words: dioxin; resveratrol; CYP1A1; CYP1B1; and ChIP assay.


Looking more promising but still nothing proven with humans, sometimes these releases help to attract funding for more research, but they are not proof until it says proof.

Cheers

I concur with John and if we keep Resveratrol as a topic with a nutrition component check out this article titled "Red Wine - Heart Health benefits?" - it touches on resveratrol, found in grape skins and seeds:
http://www.healthcastle.com/redwine-heart.shtmltled "
Enjoy,
Tracey

Hi Shane,
I have constantly wondered why you never offered any proof for any of your claims and today I found out why, You cut and paste them from other peoples blogs, I found this one.....

Resveratrol ultra supplements
have demonstrated to have an anti-clotting effect that prevents the formation of thrombi or blood clots in the blood vessels. The formation of thrombi that block small blood vessels is believed to be a cause of heart attacks and strokes. Resveratrol has been demonstrated to have anti-cancer effects as well. Sure you left out a couple of words and changed one or two but it is the same comments, and surprise, surprise there is no proof this is merely a comment and views site http://www.articlesbase.com/anti-aging-art...ts-1028833.html.

Check this out Shane and see if you can learn from it http://www.healthcastle.com/forum/index.php?showtopic=1562

Cheers

Now a days Resveratrol considered as the most potent anti oxidant of 21st century. Resveratrol is found in the skin of certain plants such as red grapes, raspberries, mulberries, blueberries, cranberries and red wine. It is mostly concentrated in red wine. It is known as 'phytolexin', which is produced by plants to fight the bacterial and fungal infections of the plant.

Resveratrol

Resveratrol indirectly influences weight loss by speeding up the body’s metabolism. Aside from its anti-aging properties as a result of the increased metabolism in our bodies, resveratrol interacts with our cells on a molecular level. resveratrol reviews: http://resveratrol-review123.com/Wine-Power.html

Resveratrol is a phytoalexin produced naturally by several plants when under attack by pathogens such as bacteria or fungi. Resveratrol has also been produced by chemical synthesis[1] and is sold as a nutritional supplement derived primarily from Japanese knotweed. In mouse and rat experiments, anti-cancer, anti-inflammatory, blood-sugar-lowering and other beneficial cardiovascular effects of resveratrol have been reported. Most of these results have yet to be replicated in humans.

Resveratrol is a very potent anti oxidant found in the grape plants and in berries. It is known as 'phytolexin', which is produced by plants to fight the bacterial and fungal infections of the plant. It is also a vital content of the red wine. It is very much concentrated in red wine.

Resveratrol is a phytoalexin naturally when attacked several plant pathogens such as bacteria or fungi. Resveratrol is sold as a dietary supplement derived primarily from Japanese knotweed. In mice and rat experiments, anti-cancer, anti-inflammatory, blood-sugar-lowering and other beneficial effects on the cardiovascular system on resveratrol have been reported. Most of these results have been put in man.

Has anybody used Resveratrol with proven results for the improvement of heart health, blood pressure etc? I would be very interested to know.

Hi r4revolution
Scan the entries within this topic (resveratrol) now, with the merging of information, and you will come across some clinical discussion and links to relevant articles.
Enjoy the information,
Tracey