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Newly Published Evidence Suggests Concord Grape Juice May Inhibit Formation of Breast Cancer Tumors
Animal Study Indicates Role of Concord Grape Juice in Chemoprevention
CONCORD, Mass., March 13 /PRNewswire/ -- Drinking Concord grape juice inhibited the formation of breast tumors in laboratory rats while also reducing the amount of DNA damage to mammary glands, according to a study published in a recent issue of Cancer Letters.
"This study looked at the early, or initiation, stage of cancer development and saw that consuming Concord grape juice actually suppressed the growth of tumors as well as reduced damage to the mammary gland's DNA," explained study senior author, Keith Singletary, Ph.D., Professor of Nutrition, Department of Food Science & Human Nutrition, University of Illinois. "In a related previous study, we saw a similar effect in what we call the promotion stage-a later stage in the development of cancer. Taken together, the results are quite interesting and certainly merit additional study."
"These studies indicate that specific constituents or combinations of phytochemicals in Concord grape juice can block the initiation stage of tumor formation," Singletary explained. Cancer develops over an extended period of time in at least two stages -- initiation and promotion. The initiation, or early stage of cancer, may occur when there is damage to a cell's DNA resulting from a variety of factors including the exposure to carcinogens or to oxygen free radical species. The promotion stage occurs when these "initiated" cells are then stimulated to reproduce faster than surrounding normal cells. "With the results of this study combined with the previous one, we see Concord grape juice having a suppressive effect on both stages of cancer development," Singletary said.
Animal Study Indicates Role of Concord Grape Juice in Chemoprevention
CONCORD, Mass., March 13 /PRNewswire/ -- Drinking Concord grape juice inhibited the formation of breast tumors in laboratory rats while also reducing the amount of DNA damage to mammary glands, according to a study published in a recent issue of Cancer Letters.
"This study looked at the early, or initiation, stage of cancer development and saw that consuming Concord grape juice actually suppressed the growth of tumors as well as reduced damage to the mammary gland's DNA," explained study senior author, Keith Singletary, Ph.D., Professor of Nutrition, Department of Food Science & Human Nutrition, University of Illinois. "In a related previous study, we saw a similar effect in what we call the promotion stage-a later stage in the development of cancer. Taken together, the results are quite interesting and certainly merit additional study."
"These studies indicate that specific constituents or combinations of phytochemicals in Concord grape juice can block the initiation stage of tumor formation," Singletary explained. Cancer develops over an extended period of time in at least two stages -- initiation and promotion. The initiation, or early stage of cancer, may occur when there is damage to a cell's DNA resulting from a variety of factors including the exposure to carcinogens or to oxygen free radical species. The promotion stage occurs when these "initiated" cells are then stimulated to reproduce faster than surrounding normal cells. "With the results of this study combined with the previous one, we see Concord grape juice having a suppressive effect on both stages of cancer development," Singletary said.
Some evidence that finishing your yummy grape juice can be good for you.
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